UNEP Chemicals works to protect humans and the environment from adverse effects caused by chemicals throughout their lifecycle, and hazardous waste. It is the focal point of UNEP activities on chemicals issues and the main catalytic force in the UN system for concerted global action on the environmentally sound management of hazardous chemicals.

UNEP Chemicals' program reflects global priorities identified by governments. It works directly with countries to build national capacity for the clean production, use and disposal of chemicals, and promotes and disseminates state-of-the-art information on chemical safety. In response to mandates from UNEP's Governing Council, it facilitates global action, including the development of international policy frameworks, guidelines and programs, to reduce and/or eliminate risks from chemicals.

In delivering policy and technical assistance for the sound management of chemicals, UNEP Chemicals builds and strengthens partnerships with governments, organisations like the OECD, and non-governmental organisations. It also works closely with agencies within the UN family, including WHO, FAO, UNIDO, ILO, UNITAR, UNDP and the World Bank, and with the secretariats of the Basel, Rotterdam and Stockholm conventions on chemicals and wastes.